MHS MesoHair Solution 12 from the Medline Organic line by DSD de Luxe is a treatment against hair loss for scalp mesotherapy. It combines three biomimetic growth factors with copper tripeptide-1, 18 amino acids, coenzymes, nucleotides and vitamins. Here you will learn what these ingredients do and which studies stand behind them. Important: the studies were carried out with the individual ingredients, not with MesoHair Solution itself. This is a cosmetic product; if hair loss is severe or sudden, please have the cause checked by a doctor.
Key facts at a glance
- VEGF (sh-Polypeptide-9) improves the blood supply to the hair follicle – in studies, hair grew faster and thicker.
- IGF-1 (sh-Oligopeptide-2) is a central regulator of hair growth and keeps follicles in the growth phase.
- bFGF (sh-Polypeptide-1) belongs to the FGF family, which accelerated the start of the growth phase in studies.
- Copper tripeptide-1 (GHK-Cu) enlarged hair follicles in animal studies and turned fine vellus hair into stronger hair.
- Microneedling with a mesoroller or dermapen improves the uptake of actives into the scalp – clearly so in a study with 100 men.
VEGF (sh-Polypeptide-9): better supply to the hair root
VEGF (vascular endothelial growth factor) stimulates the formation of fine blood vessels. The hair follicle is one of the most metabolically active tissues in the body and needs plenty of oxygen and nutrients. In a study in the Journal of Clinical Investigation, more VEGF enlarged the blood vessels around the follicle by over 40 %, hair regrew faster after removal, and hair bulbs and hair shafts became more than 30 % thicker. When VEGF was blocked, hair grew more slowly and follicles became thinner [1]. The authors describe this as the first direct evidence that a better blood supply promotes hair growth.
IGF-1 (sh-Oligopeptide-2): signal for the growth phase
IGF-1 (insulin-like growth factor 1) is produced by the cells of the dermal papilla themselves. In a study on cultured human hair follicles, IGF-1 proved to be an important regulator of hair growth even at natural concentrations and kept follicles in the growth phase (anagen) [2]. sh-Oligopeptide-2 is a biotechnologically produced peptide modelled on IGF-1.
bFGF (sh-Polypeptide-1): starting the growth phase
bFGF (basic fibroblast growth factor) belongs to the family of fibroblast growth factors. It stimulates cell renewal and the formation of collagen and elastin. In a study in mice, growth factors of the FGF family accelerated the transition of hair follicles into the growth phase – via the β-catenin and Sonic Hedgehog pathways, which are crucial for forming new hair [3].
Copper tripeptide-1 (GHK-Cu): stronger follicles
Copper tripeptide-1, also called GHK-Cu, is a peptide naturally found in the body that binds copper. It is best known for its regenerating effect on the skin: it promotes collagen formation and influences numerous tissue-repair genes [4].
For hair, animal studies are the best documented: copper peptides increased cell division in the hair follicle, enlarged follicles and turned fine vellus hair into stronger terminal hair; the growth phase lasted longer [5]. In mice with chemotherapy-induced hair loss, copper peptides protected against shedding and accelerated regrowth [6]. In a controlled study with 30 patients after hair transplantation, fewer transplanted hairs fell out with copper peptide (10 % instead of 30 %), the scalp healed faster and new hair grew earlier [7].
To be honest: large clinical studies on GHK-Cu for hair loss do not exist yet. The laboratory and animal data are convincing, however, and in MesoHair Solution the peptide works together with the growth factors.
Amino acids, coenzymes and vitamins
Hair consists of around 90 % keratin – a protein built from amino acids, especially the sulphur-containing amino acid cystine. MesoHair Solution provides 18 amino acids (incl. cystine, methionine, arginine, glutamine), coenzymes (NAD, FAD, coenzyme A) that support the energy supply of the metabolically active follicle cells, nucleotides for cell division, glutathione and vitamins C and E as antioxidants, plus a vitamin B complex with biotin and niacinamide.
Microneedling: so the actives arrive
Microneedling with a mesoroller or dermapen creates tiny channels in the scalp. They improve the uptake of actives and additionally trigger the body's own regeneration processes. In a randomised study with 100 men with androgenetic hair loss, weekly microneedling (1.5 mm) combined with a hair-growth product led to clearly more new hair after 12 weeks than the product alone [8]. A 2025 study confirmed: microneedling with growth-factor-rich plasma (PRP) clearly increased hair density and thickness [9].
Important: at home, use a mesoroller or dermapen only after professional training and with sterile instruments.
How to use MesoHair Solution 12
Wash hair with a DSD de Luxe shampoo, treat the scalp with a mesoroller or dermapen, spread the contents of one ampoule (5 ml) over the entire scalp and massage in. Leave on for 24 hours, then rinse. Month 1: 1 ampoule per week, months 2 and 3: every 15 days, then for maintenance every 2 months. Optimal results after 3 months.
